修饰抗体 Products
酪氨酸磷酸化抗体偶联树脂
杭州景杰生物科技有限公司
Anti-phosphotyrosine antibody conjugated agarose beads

Cat#:

PTM-703

Ab Type:

P/M

Applications:

IAC IP

Species:

All

Price: (0.5 ml)

16941.00

Price: (0.1 ml)

 5000.00


Product Description

The rabbit-derived polyclonal anti-phosphotyrosine antibodies are cross-linked to agarose with stable amide linkages. In the global proteomic screening of tyrosine phosphorylation, this product was well utilized as affinity matrix to specifically capture the peptides/proteins bearing tyrosine phosphorylated residues.  


Source/Purification

/


Specificity

/

Recommended Applications

Protein/peptide immunoprecipitation for tyrosine phosphorylation proteomics; Immuno-affinity chromatography.  


Recommended antibody dilution

/

Important

/

Scientific Description

Tyrosine phosphorylation plays an important role in multiple pathophysiological conditions. It has been well documented that unregulated tyrosine kinase activity may lead to malignancy and tumor formation by impacting phosphotyrosine status of protein targets. Therefore, systematical screening of phosphotyrosine substrates in pathophysiological conditions is a fundamental mission to screen biomarkers and develop effective drugs in phosphotyrosine-mediated diseases. To address this, the affinity chromatography with anti-phosphotyrosine antibody beaded agarose followed by MS/MS identification is viewed as the most preferable and efficient method.  

Storage & Stability

Store product at -20oC. Avoid repeated freeze/thaw. Antibody is supplied in PBS with 50% glycerol and 0.01% sodium azide.Stable for 12 months from date of receipt.


**Research purposes only. Not intended to be used for therapeutic or diagnostic purposes in humans or animals.

 


Protein/peptide immunoprecipitation for tyrosine phosphorylation proteomics; Immuno-affinity chromatography.  

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