修饰抗体 Products
赖氨酸丙二酰化抗体偶联树脂
杭州景杰生物科技有限公司
Anti-malonyllysine antibody conjugated agarose beads

Cat#:

PTM-904

Ab Type:

P

Applications:

IAC IP

Species:

All

Price: (0.5 ml)

22432.00

Price: (0.1 ml)

 7800.00


Product Description

The rabbit-derived polyclonal anti-malonyllysine antibodies are crosslinked to agarose with stable amide linkages. In the global proteomic screening of lysine malonylation, the product was well utilized as affinity matrix to specifically capture the peptides/proteins bearing malonyllysine residues in all species.


Source/Purification

/


Specificity

All

Recommended Applications

Protein/peptide immunoprecipitation for lysine malonylation proteomics; Immuno-affinity chromatography.


Recommended antibody dilution

/

Important

/

Scientific Description

Malonylation of lysine is a newly identified reversible modification controlling protein activity. Sirt5, a regulatory enzyme for lysine malonylation, can catalyze lysine demalonylation reactionsin vivo and in vitro. With integrated proteomic approaches and biochemistry analysis, lysine malonylation has been well demonstrated in both prokaryotes and eukaryotes in wide ranges of proteins including histones and non-histone substrates. Lysine malonylation may provide a new paradigm in the cellular regulation, such as energy metabolism in diverse organisms.


Storage & Stability

Store product at -20oC. Avoid repeated freeze/thaw. Antibody is supplied in PBS with 50% glycerol and 0.01% sodium azide.Stable for 12 months from date of receipt.


**Research purposes only. Not intended to be used for therapeutic or diagnostic purposes in humans or animals.


Protein/peptide immunoprecipitation for lysine malonylation proteomics; Immuno-affinity chromatography.

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